Immune System, Skin Microbiome ‘Complement’ One Another

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Researchers from the Perelman School of Medicine at the University of Pennsylvania demonstrate for the first time that the immune system influences the skin microbiome. A new study found that the skin microbiome — a collection of microorganisms inhabiting the human body — is governed, at least in part, by an ancient branch of the immune system called complement. In turn, it appears microbes on the skin tweak the complement system, as well as immune surveillance of the skin. They found that complement may, in part, be responsible for maintaining a diverse set of microbes on our skin and keeping our skin healthy, which could play a role in a host of skin diseases.

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