SKINOMICS: Transcriptional Profiling in Dermatology and Skin Biology

Melanoma

Recent years witnessed the birth of bioinformatics technologies, which greatly advanced biological research. These ‘omics’ technologies address comprehensively the entire genome, transcriptome, proteome, microbiome etc. A large impetus in development of bioinformatics was the introduction of DNA microarrays for transcriptional profiling. Because of its accessibility, skin was among the first organs analyzed using DNA microarrays, and dermatology among the first medical disciplines to embrace the approach. Here, DNA microarray methodologies and their application in dermatology and skin biology are reviewed.

To access to the full artice: Skinomics: Transcriptional Profiling in Dermatology and Skin Biology (Image adopted from http://boston.cityscienceclub.com/2012/09/21/pigment-mutation-a-likely-key-to-detecting-skin-cancer/)

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